Green Synthesis of N-pyrroles in Water via Using ZrOCl2.8H2O as an Efficient and Eco-Friendly Catalyst
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Abstract:
A simple and efficient protocol for the synthesis of N-substituted pyrroles from one-pot condensation reaction of 2, 5-dimethoxytetrahydrofuran with aryl/alkyl, sulfonyl and acyl amines in the presence of ZrOCl2•8H2O in water has been developed. This new method has the advantages of simple experimental and work-up procedure, high to excellent yields, easy availability, economical, eco-friendly of the catalyst and high catalytic activity.
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Journal title
volume 9 issue 3
pages 55- 60
publication date 2015-07-01
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